Agricultural Research Service - ARS

Dr. Duke's
Phytochemical and Ethnobotanical Databases

Chemicals and their Biological Activities in: Simarouba amara AUBL. (Simaroubaceae) -- Simaruba Bark


Chemicals

13,18-DEHYDROGLAUCARUBINE Bark: DUKE1992A
No activity reported.

2'-ACETYLGLAUCARUBINE Bark: DUKE1992A
No activity reported.

2'-ACETYLGLAUCARUBINONE Bark: DUKE1992A
No activity reported.

21,20-ANHYDROMELIANONE Bark: GMJ
No activity reported.

3,21-DIOXO-TIRUCALLA-7,24-DIENE Bark: GMJ
No activity reported.

5-HYDROXYCANTHIN6-ONE Bark: DUKE1992A
No activity reported.

ALKALOIDS Bark 5,000 - 8,000 ppm DUKE1992A
No activity reported.

EO Bark 1,000 - 1,800 ppm DUKE1992A
No activity reported.

MELIANONE Bark: DUKE1992A
No activity reported.

OXO-3-TIRUCALLA-7,24-DIENE Bark: GMJ
No activity reported.

RESIN Bark: DUKE1992A
No activity reported.

SIMAROLIDE Bark: DUKE1992A
No activity reported.

SIMARUBIDIN Bark 500 ppm; DUKE1992A
No activity reported.

SIMARUBIN Bark 10,000 ppm; DUKE1992A
No activity reported.

SIMARUBOLIDE Bark: DUKE1992A
No activity reported.

TANNIN Bark 200,000 - 270,000 ppm DUKE1992A
Anthelminthic JNP59:205 ; Antibacterial JE26:74 ; Anticancer JAF47:397 ; Anticariogenic JNP59:205 ; Antidiarrheic DUKE1992B ; Antidysenteric DUKE1992B ; Antihepatotoxic JNP59:205 ; AntiHIV JNP59:205 ; Antihypertensive JNP59:205 ; Antilipolytic JNP59:205 ; Antimutagenic DUKE1992B ; Antinephritic CPB38:1049 ; Antiophidic EMP5:363 ; Antioxidant 1/3 quercetin JAF47:397 IC50=1.44 ug/ml CPB38:1051 ; Antiradicular 1/3 quercetin JAF47:397 500 mg/kg/day orl mus CPB38:1049 ; Antirenitic CPB38:1049 ; Antitumor; Antitumor-Promoter JAF47:397 ; Antiulcer JNP59:205 ; Antiviral; Cancer-Preventive HG22:14 ; Carcinogenic AHP156 ; Chelator JNP59:205 ; Cyclooxygenase-Inhibitor JNP59:205 ; Glucosyl-Transferase-Inhibitor JNP59:205 ; Hepatoprotective DUKE1992B ; Immunosuppressant RWG29 ; Lipoxygenase-Inhibitor JNP59:205 ; MAO-Inhibitor JNP59:205 ; Ornithine-Decarboxylase-Inhibitor JNP59:205 ; Pesticide DUKE1992B ; Psychotropic CPB38:1049 ; Xanthine-Oxidase-Inhibitor JNP59:205

TIRUCALLA-7,24-DIENE-3,21-DIONE Plant: DUKE1992A
No activity reported.

TIRUCALLA-7,24-DIENE-3-ONE Plant: DUKE1992A
No activity reported.

References

AHP156: Jim Duke's personal files
CPB38:1049: Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
CPB38:1051: Jim Duke's personal files
DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.
EMP5:363: Economic & Medicinal Plant Research, 5: 363.
GMJ: Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
HG22:14: HerbalGram No. 22 - Spring 1990, page 14.
JAF47:397: Jim Duke's personal files
JE26:74: Jim Duke's personal files
JNP59:205: Jim Duke's personal files
RWG29: Jim Duke's personal files

ppm = parts per million
tr = trace

Phytochemical Database, USDA - ARS - NGRL, Beltsville Agricultural Research Center, Beltsville, Maryland
Thu May 16 16:22:24 EDT 2002

Please send questions and comments to:

James A. Duke (E-Mail: JimDuke@cpcug.org)
or
Stephen M. Beckstrom-Sternberg (E-Mail: SteveBS@nhgri.nih.gov)

Please send technical questions and comments to:

WebMaster (E-Mail: WebMaster@ars-grin.gov)

The USDA does not recommend self diagnosis or self medication. Please see the disclaimer for more information.