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Guaco Powder Mikania guaco1 Pound (16 oz) Buy Now
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Raintree's guaco leaf powder (Mikania guaco) has been milled into a fine powder which is suitable to stuff into capsules or to prepare your own teas, tinctures or extracts. It has been sustainably wild-harvested in the Brazilian Amazon and it is rich in active and beneficial phytochemicals that occur naturally in this plant. Guaco is a significant source of the natural plant chemical, coumarin (as high as 11% in some guaco plants). Coumarin is used to produce the commonly used anticoagulant and blood thinning drug called coumadin.* Besides courmarin, other active plant chemicals in guaco include caffeolylquinic acids, cinnamic acid, glycosides, kaurenoic acids, germacran-olides, stigmasterol, tannins, and resins.* To see pictures of guaco, click here.
Traditional Uses:* for upper respiratory problems (coughs, bronchitis, colds/flu, asthma, allergies, etc.); for various internal and external bacterial and protozoal infections; for Candida and yeast infections; for snakebite and insect bites and stings; as an analgesic (pain-reliever) and anti-inflammatory for arthritis, rheumatism, intestinal inflammation, and ulcers
For more information about guaco (Mikania guaco), please refer to the Database File for Guaco in the Tropical Plant Database. For general information on Raintree's available bulk plants and sustainable harvesting practices, please refer to Main Page for Bulk Plants.
This bulk one pound package retails for $28.00.
Purchase Guaco Powder Now
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Ingredients: 100% pure guaco leaf (Mikania guaco). No binders, fillers or additives are used. It is a wild harvested product—grown naturally in the Brazilian Amazon without any pesticides or fertilizers.
Suggested Use: This plant is best prepared as an infusion (tea). Use one teaspoon of powder for each cup of water. Pour boiling water over herb in cup and allow to steep 10 minutes. Strain tea (or allow settled powder to remain in the bottom of cup) and drink warm. It is traditionally taken in 1/2 cup amounts, 3-4 times daily. For more complete instructions, see the Preparation of Herbal Remedies article.
Contraindications: Guaco contains a significant amount of coumarin which is the plant chemical coumadin drugs are derived from. Coumarin/coudamin has an anti-coagulant and blood thinning effect and the use of guaco may demonstrate anticoagulant effects due to the coumarin content. Consult with your physician before taking this plant if you are taking coumadin drugs or if coumadin anticoagulant type drugs are contraindicated for your condition.
Drug Interactions: Will potentiate or enhance the effect of Warfarin® and other coumadin drugs.
Other Observations: In large dosages (three times or more the suggested use above) guaco has been reported to cause nausea, vomiting, and diarrhea.
RELATED PRODUCTS:
Guaco can be found in these proprietary Raintree products:
Third-Party Published Research*
This Raintree product has not been the subject of any clinical research.
All available third-party research on guaco can be found at PubMed.
A partial listing of the published research on guaco is shown below:
Anti-Allergy, Cough Suppressant, Bronchodilator, & Expectorant Actions:
dos Santos, S. C., et al. "LC characterisation of guaco medicinal extracts, Mikania laevigata and M. glomerata, and their effects on allergic pneumonitis." Planta Med. 2006 Jun; 72(8): 679-84.
Soares de Moura, R., et al. “Bronchodilator activity of Mikania glomerata Sprengel on human bronchi and guinea-pig
trachea.” J. Pharm. Pharmacol. 2002; 54(2): 249-56.
Fierro, I. M., et al. “Studies on the anti-allergic activity of Mikania glomerata.” J. Ethnopharmacol. 1999; 66(1): 19-24.
Leite, M. G. R., et al. “Actividade bronchodilatora de Mikania glomerata, Justicia pectoralis e Torresea cearensis."
Simposio de Plantas Medicinais do Brazil. December 1992. Curitiba. Resumos. p. 21.
Oliveira, F., et al. “Caraterizacao cromatograpfica do extracto fluido de Mikania glomerata Sprengel.” Simposio de Plantas
Medicinais do Brazil. December 1992. Curitiba. Resumos. p. 96.
Anti-ulcer Actions:
Bighetti, A. E., et al. “Antiulcerogenic activity of a crude hydroalcoholic extract and coumarin isolated from Mikania
laevigata Schultz Bip.” Phytomedicine. 2005 Jan; 12(1-2): 72-7.
Paul, R. K., et al. “Antiulcer activity of Mikania cordata.” Fitoterapia. 2000 Dec; 71(6): 701-3.
Mosaddik, M. A., et al. “The anti-ulcerogenic effect of an alkaloidal fraction from Mikania cordata on diclofenac
sodium-induced gastrointestinal lesions in rats.” J. Pharm. Pharmacol. 2000 Sep; 52(9): 1157-62.
Bishayee, A., et al. “Protective effects of Mikania cordata root extract against physical and chemical factors-induced gastric
erosions in experimental animals.” Planta Med. 1994 Apr; 60(2): 110-3.
Blood Thinning Actions:
Biavatti, M. W., et al. “Coumarin content and physicochemical profile of Mikania laevigata extracts.” Z. Naturforsch. 2004;
59(3-4): 197-200.
Cabral, L. M., et al. “Development of a profitable procedure for the extraction of 2-H-1- benzopyran-2-one (coumarin) from
Mikania glomerata." Drug. Dev. Ind. Pharm. 2001; 27 (1): 103-6.
Oliveira, F., et al. "Isolation and identification of chemical components of Mikania glomerata Sprengel and Mikania
laevigata Schultz Bib ex Baker.” Rev. Rarm. Bioquim. 1984; 20(2): 169-83.
Antivenin Actions:
Maiorano, V. A., et al. “Antiophidian properties of the aqueous extract of Mikania glomerata.” J. Ethnopharmacol. 2005 Dec;
102(3): 364-70.
Ruppelt, B. M., et al. “Pharmacological screening of plants recommended by folk medicine as anti-snake venom--I. Analgesic
and anti-inflammatory activities.” Mem. Inst. Oswaldo Cruz. 1991; 86 Suppl 2:203-5.
Antimicrobial, Insecticidal & Antiprotozoal Actions:
dos Santos, S. C., et al. "LC characterisation of guaco medicinal extracts, Mikania laevigata and M. glomerata, and their effects on allergic pneumonitis." Planta Med. 2006 Jun; 72(8): 679-84.
Betoni, J. E., et al. "Synergism between plant extract and antimicrobial drugs used on Staphylococcus aureus diseases." Mem. Inst. Oswaldo Cruz. 2006 Jun; 101(4): 387-90.
Yatsuda, R., et al. “Effects of Mikania genus plants on growth and cell adherence of Mutans streptococci.” J. Ethnopharmacol.
2005; 97(2): 183-9.
Duarte, M. C., et al. “Anti-Candida activity of Brazilian medicinal plants.” J. Ethnopharmacol. 2005; 97(2): 305.
Holetz, F. B. “Screening of some plants used in the Brazilian folk medicine for the treatment of infectious diseases.” Mem. Inst. Oswaldo Cruz. 2002 Oct; 97(7): 1027-31
Rungeler, P., et al. “Germacranolides from Mikania guaco." Phytochemistry 2001; 56(5): 475-89.
Muelas-Serrano, S., “In vitro screening of American plant extracts on Trypanosoma cruzi and Trichomonas vaginalis.” J.
Ethnopharmacol. 2000; 71(1-2): 101-7.
Rojas de Arias A., et al. “Mutagenicity, insecticidal and trypanocidal activity of some Paraguayan Asteraceae.” J.
Ethnopharmacol. 1995; 45(1): 35-41.
Davino, S. C., et al. “Antimicrobial activity of kaurenoic acid derivatives substituted on carbon-15.” Braz. J. Med. Biol. Res.
1989; 22(9): 1127-9.
Anti-inflammatory & Pain-Relieving Actions:
Suyenaga, E. S., et al. “Antiinflammatory investigation of some species of Mikania." Phytother. Res. 2002; 16(6): 519-23.
Ahmed, M., et al. “Analgesic sesquiterpene dilactone from Mikania cordata.” Fitoterapia. 2001 Dec; 72(8): 919-21.
Peluso, G., et al. “Studies on the inhibitory effects of caffeoylquinic acids on monocyte migration and superoxide ion
production.” J. Nat. Prod. 1995; 58(5): 639-46.
Leite, M. G. R., et al. “Actividade bronchodilatora de Mikania glomerata, Justicia pectoralis e Torresea cearensis."
Simposio de Plantas Medicinais do Brazil. December 1992. Curitiba. Resumos. p. 21
Oliveira, F., et al. “Caraterizacao cromatograpfica do extracto fluido de Mikania glomerata Sprengel.” Simposio de Plantas
Medicinais do Brazil. December 1992. Curitiba. Resumos. p. 96
Ruppelt, B. M., et al. “Pharmacological screening of plants recommended by folk medicine as anti-snake venom--I.
Analgesic and anti-inflammatory activities.” Mem. Inst. Oswaldo Cruz. 1991; 86 Suppl 2:203-5.
Antimutagenic (cancer preventative) Actions:
Fernandes, J. B., et al. ”Mutagenic and antimutagenic potential of the medicinal plants M. laevigata and C. xanthocarpa.”
Phytother. Res. 2003; 17(3): 269-73.
Bishayee A, “Anticarcinogenic biological response of Mikania cordata: reflections in hepatic biotransformation systems.”
Cancer Lett. 1994 Jun; 81(2): 193-200.
Fertility Actions:
Graca, C., et al. "Mikania laevigata syrup does not induce side effects on reproductive system of male Wistar rats." J. Ethnopharmacol. 2006 Nov 12;
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* The statements contained herein have not been evaluated
by the Food and Drug Administration.
This product is
not intended to treat, cure, mitigate or prevent any disease.
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Last updated 3-20-2010
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